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 MEDICAL

There are various drugs for the treatment of different diseases.

The Liver diseases have been listed down in alphabetical order. Click on the alphabet to read more about the diseases.

 
A
B
 
Wilson's disease Contraindications and side effects of medications
 

Wilson’s disease

Treatment Indication Dose
Penicillamine Promotes removal of excess copper in the urine.

250 to 500 mg by mouth given in 2-4 divided doses daily thenincrease dose by 250 mg every 4-7 days to a maximum of 1,000 to 1,500 mg for 4-6 months. Then 750 to 1,000 mg by mouth given in two divided doses daily. The drug should be taken ideally one hour before or two hours after meals.

Trientene Promotes removal of excess copper in the urine. 750 to 1500 mg by mouth given in 2-3 divided doses daily for 4-6 months. Then 750 to 1,000 mg by mouth given in 2-3 divided doses daily. The usual dose in children is 20 mg per kg of body weight given in 2-3 divided doses rounded to the nearest 250 mg. The drug should be taken ideally one hour before or two hours after meals.
Zinc Used in patients who (i) cannot tolerate penicillamine or trientene (ii) brain-related symptoms that is not responding to penicillamine or trientene, and (iii) maintenance treatment for those who have been successfully decoppered with penicllamine or trientene. 150 mg by mouth given in three divided doses daily.In children, administer 75 mg by mouth given in three divided doses daily.
   


Contraindications and side effects of medications

Medication Reasons not to take this medicine Side effects
Unfractionated Heparin If you have an allergy to heparin or any part of this medication.

If you have low blood platelet levels.

If you are actively bleeding

Bleeding problems

Chest pain

Fevers, chills

Headache

Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

Bruising

Low platelet counts can rarely occur

Low Molecular weight Heparin If you have an allergy to low molecular weight heparin or any part of this medication.

If you have low blood platelet levels.

If you are actively bleeding
Bleeding problems

Chest pain

Fevers, chills

Headache

Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

Bruising

Low platelet counts can rarely occur.
Warfarin If you have an allergy to warfarin or any other part of this medicine.

If you have any of the following conditions: Anesthesia given in your spine, aneurysm, bleeding problems, cancer, diverticulitis, heart valve infection, liver disease, low platelet count, pericarditis, polyarthritis, poor nutrition, recent surgery of the eye or brain, uncontrolled high blood pressure, unsteadiness, or warfarin-induced necrosis.

If you know that you will not take the medicine as directed.

If you are pregnant or may be pregnant.
Bleeding problems.

Headache.

Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
Allopurinol If you have an allergy to allopurinol or any other part of this medicine. Skin irritation.
Potassium Citrate If you have an allergy to potassium citrate or any other part of this medicine.

If you have any of the following conditions: Adynamia episodica hereditaria, dehydration, heat cramps, high potassium levels, poor kidney function, or untreated Addison's disease.
High potassium level. Signs include feeling weak, lightheaded, dizzy, feel like passing out, or have numbness or tingling.

Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

Diarrhea.

Belly pain.

Gas.
Angiotensin converting enzyme inhibitor If you have an allergy to enalapril or any other part of this medicine.

If you have any of the following conditions: Blockage in the kidneys' arteries or other kidney disease, or hyperaldosteronism.

If you are pregnant or may be pregnant.
Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

Headache.

Abnormal taste. This is usually reversible.

Cough.
Granulocte colony stimulating factor If you have an allergy to filgrastim or any other part of this medicine.

If you are taking chemotherapy and radiation treatments at the same time.
Bone pain.

Headache.

Short-term discomfort after use.

Feeling tired or weak.

Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
Nitisinone If you have an allergy to nitisinone or any other part of this medicine. Hair loss.

Skin irritation.

Low platelet and white blood cell counts can rarely occur.
Desmopressin Do not give this medicine to a child younger than 6 years of age.

If you have an allergy to desmopressin acetate or any other part of this medicine.
Headache.

Belly pain.

Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
Von Willebrand Factor concentrates If you have an allergy to Von Willebrand factor or any other part of this medicine. Blood clots.
Aminocaproic acid If you have an allergy to aminocaproic acid or any other part of this medicine. Headache.

Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
Belly pain.

Nasal congestion.
Tranexaminic acid If you have an allergy to tranexaminic acid or any other part of this medicine.

If you are color-blind.
Blurry vision.

Blood clots.

Very low blood pressure.

Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

Belly pain
Topical thrombin If you have an allergy to thrombin or any other part of this medicine. Fever.

Allergic reaction.
Intravenous immune globulin If you have an allergy to immune globulin or any other part of this medicine.

If you have IgA deficiency.
Pain or irritation where the shot is given.

Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

Headache.
Penicillamine If you have an allergy to penicillamine or any other part of this medicine.

If you are pregnant or may be pregnant.

If you are breast-feeding.
Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

Abnormal taste.

This is usually reversible.

Not hungry.
Muscle weakness.

Itching.
Trientene If you have an allergy to trientine or any other part of this medicine.

If you have any of the following conditions: Biliary cirrhosis, cystinuria, or rheumatoid arthritis.
Abnormal taste. This is usually reversible.

Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

Not hungry.
Zinc   Dizziness.

Restlessness.

Diarrhea.

Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

Stomach ulcers.
   

Mg = milligram
Mcg = microgram
Kg = kilogram
Intravenous administration = given as a shot in the vein
Subcutaneous administration = given as a shot in the fatty part of the skin
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