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 MEDICAL

There are various drugs for the treatment of different diseases.

The Liver diseases have been listed down in alphabetical order. Click on the alphabet to read more about the diseases.

 
A
B
 
Von Willebrand Disease (VWD)  
 

Von Willebrand Disease (VWD)

Treatment Indication Dose
Desmopressin Increases levels of enzymes that are deficient in this condition. These enzymes are necessary for formation of blood clots.

0.3 micrograms/kg by intravenous or subcutaeous administration (maximum 20 micrograms) diluted in 50 mL of normal saline infused over 20 to 30 minutes.Alternative is 150-300 micrograms by intranasal spray (1 spray in each nostril).

Von Willebrand factor concentrates Direct replacement of deficient clotting factors are indicated in more severe types of this disease (Type 3 VWD and severe Type 2a and 2b VWD). 20 to 30 International Units per kg of body weight by intravenous infusion as labeled to raise the plasma concentration of ristocetin factor to 50 to 100 percent.
Aminocaproic acid Used to prevent the breakdown of blood clots. 50 mg per kg of body weight by mouth or by intravenous injection four times a day.
Tranexaminic acid Used to prevent the breakdown of blood clots, and thereby decrease bleeding. 25 mg per kg of body weight by mouth or by intravenous injection three times a day.
Topical thrombin Used to control minor bleeding 1000-2000 units per milliliter of solution by direct application to bleeding area. Use 100 units per milliliter for bleeding from skin or mucosal surfaces
Intravenous immune globulin (IVIG) Used in patients with VWD who have not responded well to desmopressin and also have another autoimmune condition. 1 gm per kg of body weight by intravenous administration once daily for two days.
   
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