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 MEDICAL

There are various drugs for the treatment of different diseases.

The Liver diseases have been listed down in alphabetical order. Click on the alphabet to read more about the diseases.

 
A
B
 
Alagille Syndrome Alcoholic Liver Disease
Autoimmune Hepatitis

Alpha-1-Antitrypsin Deficiency

 

Alagille Syndrome

Treatment Indication Dose
Ursodeoxycholic acid May improve symptoms and laboratory abnormalities in some cases

10 mg per kg of body weight by mouth once daily

   

Alcoholic Liver Disease

Treatment Indication Dose
Corticosteroids Beneficial for severe disease as defined by laboratory values. Oral prednisolone is preferred to prednisone

40 mg by mouth once daily then taper dose down

Pentoxfylline There is some recent evidence that treatment with this immune system suppressant may be beneficial, although more studies are needed to confirm this 400 mg by mouth three times a day
Infliximab There is some recent evidence that treatment with this immune system suppressant may be beneficial, although more studies are needed to confirm this 10 mg per kg of body weight by intravenous injection once daily
   


Autoimmune Hepatitis

Treatment Indication Dose
Corticosteroids Generally instituted

(a) To control symptoms

(b) When laboratory measurements of liver function are elevated, or

(c) Abnormalities are noted on pathology specimens. Note: In patients with hepatitis C, treatment with steroids is started first before treating the viral hepatitis

60 mg by mouth once daily for 7 days, then 40 mg by mouth once daily for 7 days then 30 mg by mouth once daily for 14 days. Then 20 mg by mouth once daily

Azothioprine May be used in patients with high risk of side effects from corticosteroids. Combined therapy with corticosteroids can allow lowering the dose of corticosteroids 50 mg by mouth once daily. If used in combination with steroids then 30 mg by mouth once daily
Cyclosporine Alternative in children with high risk of side effects from corticosteroids 4 mg per kg of body weight by mouth once daily for 2-3 days then increase dose every 2-3 days to achieve a whole blood concentration of 250 +/- 50 mg/mL for the first three months
   

 

Alpha-1-Antitrypsin Deficiency

Treatment Indication Dose
IV AAT augmentation More studies are needed to confirm the benefit of replacing deficiency of Alpha-1 Antitrypsin. Not currently available in India

 

   

 

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